Annual Review of Pharmacology and Toxicology-Volume 48, 2008

The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences Jean-Marc Pascussi, Sabine Gerbal-Chaloin, Cédric Duret, Martine Daujat-Chavanieu, Marie-José Vilarem, Patrick Maurel Annual Review of Pharmacology and Toxicology, Vol. 48: 1-32 (Volume publication date February 2008)
Abstract PDF (164 KB)
Mechanisms of Placebo and Placebo- Effects Across and Treatments Fabrizio Benedetti Annual Review of Pharmacology and Toxicology, Vol. 48: 33-60 (Volume publication date February 2008)
Abstract PDF (404 KB)
Pharmacotherapy for the Treatment of Choroidal Neovascularization Due to Age- Macular Degeneration Gary D. Novack Annual Review of Pharmacology and Toxicology, Vol. 48: 61-78 (Volume publication date February 2008)
Abstract PDF (113 KB)
Nicotinic Acid: Pharmacological Effects and Mechanisms of Action Andreas Gille, Erik T. Bodor, Kashan Ahmed, Stefan Offermanns Annual Review of Pharmacology and Toxicology, Vol. 48: 79-106 (Volume publication date February 2008)
Abstract PDF (833 KB)
Activation of G Protein–Coupled Receptors: Beyond Two-State Models and Tertiary Conformational Changes Paul S.-H. Park, David T. Lodowski, Krzysztof Palczewski Annual Review of Pharmacology and Toxicology, Vol. 48: 107-141 (Volume publication date February 2008)
Abstract PDF (972 KB)
Apoptin: Therapeutic Potential of an Early Sensor of Carcinogenic Transformation Claude Backendorf , Astrid E. Visser , A.G. de Boer , Rhyenne Zimmerman , Mijke Visser , Patrick Voskamp , Ying-Hui Zhang , Mathieu Noteborn Annual Review of Pharmacology and Toxicology, Vol. 48: 143-169 (Volume publication date February 2008)
Abstract PDF (328 KB)
Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation Antonella Viola, Andrew D. Luster Annual Review of Pharmacology and Toxicology, Vol. 48: 171-197 (Volume publication date February 2008)
Abstract PDF (1037 KB)
Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response Kohsuke Takeda, Takuya Noguchi, Isao Naguro, Hidenori Ichijo Annual Review of Pharmacology and Toxicology, Vol. 48: 199-225 (Volume publication date February 2008)
Abstract PDF (333 KB)
Pharmacogenetics of Anti-HIV Drugs A. Telenti, U. M. Zanger Annual Review of Pharmacology and Toxicology, Vol. 48: 227-256 (Volume publication date February 2008)
Abstract PDF (227 KB)
Epigenetics and Complex Disease: From Etiology to New Therapeutics Carolyn Ptak , Arturas Petronis Annual Review of Pharmacology and Toxicology, Vol. 48: 257-276 (Volume publication date February 2008)
Abstract PDF (119 KB)
Vesicular Neurotransmitter Transporters as Targets for Endogenous and Exogenous Toxic Substances Farrukh A. Chaudhry, Robert H. Edwards, Frode Fonnum Annual Review of Pharmacology and Toxicology, Vol. 48: 277-301 (Volume publication date February 2008)
Abstract PDF (258 KB)
Mechanism-Based Concepts of Size and Maturity in Pharmacokinetics B.J. Anderson, N.H.G. Holford Annual Review of Pharmacology and Toxicology, Vol. 48: 303-332 (Volume publication date February 2008)
Abstract PDF (336 KB)
Role of CYP1B1 in Glaucoma Vasilis Vasiliou, Frank J. Gonzalez Annual Review of Pharmacology and Toxicology, Vol. 48: 333-358 (Volume publication date February 2008)
Abstract PDF (208 KB)
Caveolae as Organizers of Pharmacologically Relevant Signal Transduction Molecules Hemal H. Patel, Fiona Murray, Paul A. Insel Annual Review of Pharmacology and Toxicology, Vol. 48: 359-391 (Volume publication date February 2008)
Abstract PDF (289 KB)
Proteases for Processing Proneuropeptides into Peptide Neurotransmitters and Hormones Vivian Hook, Lydiane Funkelstein, Douglas Lu, Steven Bark, Jill Wegrzyn, Shin-Rong Hwang Annual Review of Pharmacology and Toxicology, Vol. 48: 393-423 (Volume publication date February 2008)
Abstract PDF (592 KB)
Targeting Chemokine Receptors in HIV: A Status Report Shawn E. Kuhmann , Oliver Hartley Annual Review of Pharmacology and Toxicology, Vol. 48: 425-461 (Volume publication date February 2008)
Abstract PDF (501 KB)
Biomarkers of Acute Kidney Injury Vishal S. Vaidya , Michael A. Ferguson , Joseph V. Bonventre Annual Review of Pharmacology and Toxicology, Vol. 48: 463-493 (Volume publication date February 2008)
Abstract PDF (386 KB)
The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy Matthew D. Hall , Mitsunori Okabe , Ding-Wu Shen , Xing-Jie Liang , Michael M. Gottesman Annual Review of Pharmacology and Toxicology, Vol. 48: 495-535 (Volume publication date February 2008)
Abstract PDF (435 KB) Supplemental Material
Regulation of GPCRs Endocytic Membrane Trafficking and Its Potential Implications Aylin C. Hanyaloglu , Mark von Zastrow Annual Review of Pharmacology and Toxicology, Vol. 48: 537-568 (Volume publication date February 2008)
Abstract PDF (513 KB)
PKC Isozymes in Chronic Cardiac Disease: Possible Therapeutic Targets? Eric Churchill , Grant Budas , Alice Vallentin , Tomoyoshi Koyanagi , Daria Mochly-Rosen Annual Review of Pharmacology and Toxicology, Vol. 48: 569-599 (Volume publication date February 2008)
Abstract PDF (571 KB)
G Protein–Coupled Receptor Sorting to Endosomes and Lysosomes Adriano Marchese, May M. Paing, Brenda R.S. Temple, JoAnn Trejo Annual Review of Pharmacology and Toxicology, Vol. 48: 601-629 (Volume publication date February 2008)
Abstract PDF (1114 KB) Supplemental Material
Stgic Approach to Fit-for-Purpose Biomarkers in Drug Development John A. Wagner Annual Review of Pharmacology and Toxicology, Vol. 48: 631-651 (Volume publication date February 2008)
Abstract PDF (347 KB)
Metabolomics: A Global Biochemical Approach to Drug Response and Disease Rima Kaddurah-Daouk, Bruce S. Kristal, Richard M. Weinshilboum Annual Review of Pharmacology and Toxicology, Vol. 48: 653-683 (Volume publication date February 2008)

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