E. coli: Shiga Toxin Methods and Protocols
(Methods in Molecular Medicine)

Publisher: Humana Press ISBN: 1617372641 edition 2011 PDF 326 pages 13,4 mb

A multidisciplinary panel of leading experimentalists details the key protocols for the diagnosis and study of the pathogenesis of Shiga toxin-producing Escherichia coli (STEC) and its isolated cytotoxin (Stx). Described in step–step detail, these readily reproducible techniques range from those for the diagnosis and detection of STEC bacteria in patient and animal samples, to those for studying the cellular microbiology of STEC infections, especially host-pathogen interactions and the hemolysin of STEC.

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Gastric Carcinoma – Molecular Aspects and Current Advances
Mahmoud Lotfy

ISBN 978-953-307-412-2, Hard cover, 354 pages
Publisher: InTech
Publication date: June 2011

Gastric cancer is one of the most common tumors worldwide. It has a heterogeneous milieu, where the genetic background, tumor immunology, oxidative stress, and microbial infections are key players in the multiple stages of tumorigenesis. These diverse factors are linked to the prognosis of the gastric cancer and the survival of gastric cancer patients. This book is appropriate for scientists and students in the field of oncology, gastroenterology, molecular biology, immunology, cell biology, biology, biochemistry, and pathology. This authoritative carey explains the fundamentals, providing a general overview of the principles followed more detailed explanations of these recent topics efficiently. The topics presented herein contain the most recent knowledge in gastric cancer concerning the oncogenic signaling, genetic instability, the epigenetic aspect, molecular features and their clinical implications, miRNAs, integrin and E-cadherin, carbohyd-associated-transferases, free radicals, immune cell responses, mucins, Helicobacter-pylori, neoadjuvant and adjuvant therapy, prophylactic stgy for peritoneal recurrence, and hepatic metastasis.

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Viral Gene Therapy
Ke Xu

ISBN 978-953-307-539-6, Hard cover, 450 pages
Publisher: InTech
Publication date: July 2011

The development of technologies that allow targeting of specific cells has progressed substantially in recent years for several types of vectors, particularly viral vectors, which have been used in 70% of gene therapy clinical trials. Particular viruses have been selected as gene delivery vehicles because of their capacities to carry foreign genes and their ability to efficiently deliver these genes associated with efficient gene expression. This book is designed to present the most recent advances in viral gene therapy

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Sphingolipids as Signaling and Regulatory Molecules
(Advances in Experimental Medicine and Biology)
Charles Chalfant, Maurizio Del Poeta

Publisher: Springer 2010 287 Pages ISBN: 1441967400 PDF 8 MB

This book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular , asthma, diabetes, inflammation and infectious .

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