Diffuse Parenchymal Lung Disease

S Karger Pub; 1 edition May 31, 2007 ISBN-10: 380558153X 348 pages PDF 8.16 Mb

Diffuse parenchymal lung disease (DPLD) represents a large and heterogeneous group of disorders. Although new insights into the pathogenesis and new techniques such as high-resolution-CT have led to a better understanding of DPLD, clinical management remains a challenge. This volume is designed to become a valuable aid in the diagnosis and management of DPLD. It starts with general topics such as a new classification system for DPLD, the general diagnostic approach, and clinical evaluation of the patient radiology, histological patterns and bronchoalveolar lavage. This is followed consideration of some basic aspects such as the genetics of DPLD, the principles of granuloma formation, pulmonary fibrogenesis and vasculitis, as well as novel treatment approaches. A large part of the book consists of disease-specific chapters, which discuss granulomatous disorders, idiopathic pulmonary fibrosis and other entities of idiopathic interstitial pneumonia, the collagen vascular , drug-induced infiltrative lung disease as well as orphan diffuse lung including Langerhans’ cell histiocytosis, lymphangioleiomyomatosis and pulmonary alveolar proteinosis.

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Inhaled Steroids in Asthma: Optimizing Effects in the Airways
Robert P. Schleimer

Publisher: Infоrma Hеalthcare 2010-11-21 ISBN: 0824705858 PDF 760 pages 4.31 MB

This book sums up the mechanistic basis, current status, and future prospects of steroid inhalation as the cornerstone of prophylactic asthma therapy, identifying its kinetic basis-especially the essential airway selectivity-and including a historical account of inhaled glucocorticoid development. Makes connections among the underlying pharmacology, impact of new simulation models, newly recognized molecular targets, and therapeutic outcomes of short- and long-term steroid inhalation therapy! Containing more than 1600 works cited, drawings, tables, equations, and micrographs, Inhaled Steroids in Asthma · describes the developmental history of inhaled steroids and provides general models for lung selectivity · considers the best way to select inhaled steroids · clarifies local metabolism, airway and lung uptake and retention, and other determinants of once-daily usage · addresses variations in lung deposition and total bioavailability among available steroids and formulations · surveys the dynamics of receptor gene-mediated processes · analyzes the role of chemokines in airway allergic inflammatory · discusses the effects of inhaled steroids in vivo on cell progenitors in asthma and rhinitis · details measuring airway inflammation as a guide for treatment decisions · outlines the clinical relevancy of exhaled nitric oxide in asthma · covers optimal trial design for judging antiasthmatic potency and efficacy · evaluates the safety of inhaled steroids Written more than 40 of the world’s leading authorities and investigators, Inhaled Steroids in Asthma is an authoritative reference for pulmonologists and pulmonary disease specialists; physiologists; allergists; immunologists; molecular, cell, and lung biologists; pediatricians; pharmaceutical scientists and pharmacologists; and medical school and upper-level undergraduate, graduate, and medical school students in these disciplines.

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Bronchial Asthma

Jaypee Brothers Medical Publishers (P) Ltd. 2005 ISBN-10: 8180614344 338 pages PDF 3.30 MB

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Chronic Obstructive Pulmonary Disease: Co-Morbidities and Systemic Consequences
Linda Nici and Richard ZuWallack

Humana Press 2012 ISBN: 1607616726 299 pages PDF 3,3 MB

Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide. 2020, COPD is expected to be the fifth leading cause of disability and the third leading cause of death. COPD is associated with significant co-morbid illnesses including cardiovascular disease, pulmonary vascular disease, osteoporosis, depression and thoracic malignancies. In addition, COPD patients often have systemic manifestations of their disease, including peripheral muscle dysfunction, decreased activity levels and nutritional abnormalities, all of which contribute to poor functional status, decreased quality of life and increased health care utilization. Lack of recognition and understanding of the complex interactions of these common co-morbid conditions and systemic effects often contributes to sub-optimal care for patients with COPD. Comprehensive in covering the range of co-morbidities that often accompany COPD, Chronic Obstructive Pulmonary Disease: Co-Morbidities and Systemic Consequences provides a concise, evidence-based review of the problem and its systemic manifestations.

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Approaches to Bronchitis
Marianna D. Gac

Publisher: InTech ISBN 10: 9789533077703 2011 PDF 70 pages 4.9 MB

The aim of this book is to present some recent interesting novel findings in the field of bronchitis, in supplement to Bronchitis. In particular this volume focuses on the successful use of evolving and the development of novel tools diagnosing and treating bronchitis. Contributions include clinical case studies, one outlining the impact of air pollution on bronchitis and two on the presentation and diagnosis of the respiratory eosinophilic bronchiolitis and primary ciliary dyskinesia; the development of a method for the swift detection of the infectious bronchitis virus and studies investigating the successful use of alternative medicines in the treatment of bronchitis. The editors would like to thank the authors of the chapters who have contributed to this book and hope this will book not only supplement Bronchitis but may increase interest in the subject.

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