Matrix Metalloproteinases in Tissue Remodelling and Inflammation

Matrix Metalloproteinases in Tissue Remodelling and Inflammation
(Progress in Inflammation Research)
Vincent Lagente, Elisabeth Boichot

Publisher: Birkhäuser Basel
Number Of Pages: 168
Publication Date: 2008-10
ISBN-10 / ASIN: 3764385847
ISBN-13 / EAN: 9783764385842
Binding: Hardcover

Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. MMP synthesis and functions are regulated three major mechanisms including transcriptional activation, post-transcriptional processing, and control of activity tissue inhibitors of metalloproteinases (TIMPs). Many cell types have been identified as producers of MMPs and TIMPs in a con of inflammatory processes. MMPs are involved in numerous inflammatory , including respiratory, cardiovascular and central nervous system pathologies.
This volume presents new advances in the involvement of MMPs in various associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs provides new insights in the relationship between activation of inflammatory cells and tissue remodelling and advises new therapeutic possibilities for the treatment of inflammatory .

http://uploaded.to/?id=cfglhf
http://ifile.it/upa5rcd/3764385847.rar